Austrian Thiem was 6-2, 3-6, 7-5, 5-7, 4-1 up when the men's match, which had already been halted on Friday because of bad weather, was stopped.
Daniil Medvedev and Karen Khachanov crushed second seed Dominic Thiem and third seed Alexander Zverev respectively to set up an all-Russian semi-final at the Rogers Cup in Montreal on Friday.
Move over Steffi Graf and Andre Agassi, because there's a new power couple in the world of tennis -- Stefanos Tsitsipas and Paula Badosa.
It will be the second time Nadal and Del Potro meet at Roland Garros. The previous match up saw the Spaniard beat Del Potro in straight sets in the opening round in 2007.
A summary of the second day's play at the US Open.
He will commence his Australian Open campaign against Alexander Bublik in the first round.
Images from Day 4 of the French Open, at Roland Garros, in Paris.
Sinner won in Cincinnati this week to claim his fifth title of a breakout season before the revelation that he avoided a ban over two positive tests
Kenin, Andreescu to be part of team event in Charleston in June
Juan Martin del Potro's summer renaissance continued on Monday as the unseeded Argentine advanced into the US Open quarter-finals when Austrian eighth seed Dominic Thiem quit their match with an injury.
Rafael Nadal and the world's best men's tennis players found themselves having to endure a 4 a.m. meeting in the freezing cold after fire alarms forced them to evacuate their central London hotel on Tuesday.
Jannik Sinner retained his Australian Open title with an emphatic 6-3, 7-6(4), 6-3 win over Alexander Zverev on Sunday
IMAGES from matches played at the BNP Paribas tennis tournament played in Indian Well, California, on Thursday
Austria's Dominic Thiem strained every sinew trying to cling on to the 32-year-old Spaniard and at times even gained a precarious foothold in his first Grand Slam final. But it ultimately proved a futile mission as, just like in all but two of Nadal's previous 87 matches here, the relentless Spaniard proved insurmountable, winning 6-4, 6-3, 6-2.
Rafael Nadal extended his astonishing winning run on clay to 42 consecutive sets as he reached the semi-finals of the Barcelona Open with a 6-0, 7-5 victory over Slovakia's Martin Klizan on Friday. The defending champion will face David Goffin on Saturday after the Belgian beat Spaniard Roberto Bautista 6-7(3), 6-2, 6-2.
This is the first time in 35 years that an Indian men's player beat a seeded player in a Grand Slam.
Images from Day 1 of the 2022 US Open at the USTA Billie Jean King National Tennis Center, in Flushing Meadows, New York, on Monday.
Novak Djokovic begins his hunt for a fifth Flushing Meadows crown when he meets Moldovan Radu Albot
With Nadal and Federer both skipping the tournament, Djokovic's sensational exit on Sunday after hitting a line judge in the throat with a ball opened up the field for a younger cohort of players.
Stan Wawrinka pulled off a stunning upset on Thursday, beating top-seeded Daniil Medvedev 6-4, 6-7 (7), 6-3 to reach the quarter-finals of the Moselle Open in Metz, France.
Images from Day 1 at the Australian Open.
The Serb, who turned 30 last month, will drop outside the top two for the first time since march 2011 on Monday -- quite a contrast to a year ago when his domination of men's tennis was complete after winning the French Open for the first time.
Alexander Zverev said the turning point in the four-hour thriller came when Thiem broke his serve for the first time in the third set, a break which reversed the momentum of the match.
Alexander Zverev said his energy began to fade midway through his five-sets Australian Open semi-final loss to Daniil Medvedev
Sumit Nagal becomes the first Indian in more than three decades to upset a seeded player in a Grand Slam.
Medvedev became only the fourth player in ATP history to beat the world's top three at the same tournament.
Dominic Thiem and home crowd favourite Filip Krajinovic reached the final of Novak Djokovic's tournament as the world number one broke down in tears in front of a packed 4,000 crowd on Sunday. World number three Thiem beat Grigor Dimitrov in straight sets to set up the clash with Krajinovic.
Rafael Nadal continued his impressive return from a long injury layoff with a 6-1 6-2 demolition of wildcard Jason Kubler to reach the quarter-finals at the Brisbane International on Thursday ahead of this month's Australian Open.
Former champion Garbine Muguruza suffered a second consecutive first-round exit at the French Open
Team Europe's Nadal was scheduled to take on Team World's Nick Kyrgios in his singles clash before partnering Swiss Federer to face John Isner and Jack Sock.
Rafael Nadal claimed a record-stretching 12th French Open title by beating Austrian fourth seed Dominic Thiem 6-3, 5-7, 6-1, 6-1 in a repeat of last year's final on Sunday.
A look at the records of Austria's Dominic Thiem and Spain's Rafael Nadal before their title clash at the French Open on Sunday.
Zverev made more headlines off the court than on it last year.
Rafael Nadal looked razor sharp again during his latest meeting with qualifier Thiem
IMAGES from matches on Day 8 at the French Open
Emma Raducanu's US Open victory is among the "greatest achievements" in women's sport, men's world number eight Dominic Thiem said.
Rafael Nadal won a record-extending 10th Barcelona Open title on Sunday by thrashing Dominic Thiem of Austria 6-4, 6-1, collecting his second claycourt title in a row.
Rafael Nadal, whose all-time claycourt record now stands at 414-36 says nobody should assume his feats are routine and that each victory is celebrated like the first.
Here is a quick glance of all the highs and lows from Nadal's stupendous career:
Novak Djokovic marked his return to Serbia, after being stranded in the Spanish resort of Marbella for two months due to the coronavirus lockdown, by announcing that he has organised an event which will be contested across the Balkans. When the world number one had travelled to Marbella with his family in mid-March to visit his younger brother Marko, he had no idea it would be another two months before he could return to his homeland on Sunday.
